(Bloomberg) -- Anthem Inc. has explored a takeover of its smaller health-insurance rival Cigna Corp., two people with knowledge of the matter said, with the health-insurance industry is poised for a consolidation wave.

Anthem, which has discussed its interest with Cigna, is also weighing a bid for Humana Inc., one of the people said, asking not to be identified discussing private information. In a third possible combination, Humana has also drawn interest from Aetna Inc., another person said.

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